Pregnant women if caught rubella during pregnancy, fetal rubella infection, known as congenital rubella and congenital rubella syndrome, can cause fetal multiple malformations. Most children with symptoms is already evident at birth, show only part of the case in a few weeks after birth, a few months, after a few years.
Congenital rubella organ involvement, and clinical manifestation is not the same. Newborn babies may see purple red bleeding due to thrombocytopenia spots seen due to liver disease or hemolytic jaundice, severe anaemia, pale or wax yellow, liver, spleen enlargement. Heart abnormalities are also quite common, we can see various types of congenital heart disease, such as the closure of patent ductus arteriosus, atrial septal defect, Ventricular septal defect and pulmonary stenosis or complex malformations of the heart. Eye lesions are unilateral or bilateral cataract, small eye, glaucoma, etc. If the middle ear or inner ear disease is unilateral or bilateral hearing loss may occur. Because rubella virus on neural tissue has very strong invasion force, rubella virus and longer exist in the brain, cerebral involvement clear, visible microcephaly, intellectual, movement, and behavioral developmental disorders. This shows that the severity of congenital rubella. Treatment of extremely difficult, so is mainly preventive.
Prevention is the main object of pregnant women. For the prevention of congenital rubella, some countries \' all girls to immunization with rubella vaccine, the most ideal for vaccination of school-age girls and married women. If the past had not suffered from rubella, rubella vaccine has not been vaccinated, you should first determination of rubella antibodies in serum, such as negative for rubella vaccine injection. Is a live attenuated rubella vaccine injection, it also can cause damage to the fetus. Pregnant women should not be vaccinated. If no rubella in pregnant women nor immunization with rubella vaccine, such as close contact with patients with rubella, which can be passive immunization. Placenta injection intravenous immunoglobulin as soon as possible (not less than 20 ml) or immunoglobulin (not less than 10 ml), this prevents fetal congenital rubella.
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