By the drug\'s side effects affect fertility, known as a drug-induced infertility. According to statistics, the 4%~6% of infertility is caused by drugs.
Sulfonamide compound sulfamethoxazole is often used in treating urinary tract infections, respiratory infections, tonsillitis, and so on. It side effect suppression of testicular function in fertility, significant reduction in sperm count, sperm mobility significantly lower. Liu nitrogen sulfapyridine is a drug for treatment of ulcerative colitis can also lead to lack of semen, sperm abnormal 80%, accompanied by reduced sperm count, sperm vitality reduced and infertility.
Antibiotics furacilin and its derivative inhibits testicular cell metabolism and oxygen consumption of carbohydrates, bring down the spermatogenic cells of DHA in concentrations, caused reduced sperm, leading to infertility. Macrocyclic Lactone drug, such as erythromycin, Spiramycin, McGrady Adriamycin, will cause sperm development stalled and reduced mitosis, sperm is kill or be killed, the survival of sperm activity also decreased significantly.
Cimetidine quack the drug for the treatment of duodenal ulcers, when large numbers of continued use can lead to infertility caused by reduced sperm count and. There are reports, daily oral 1200 mg, sperm count can be reduced by 43% after 9 weeks.
Hormones of long term application of excess steroid hormone, can suppress the hypothalamic-pituitary-testicular axis function in men, testicular atrophy, sperm production decrease, leading to infertility. The long-term use of steroid hormones in male athletes had been confirmed. Application of estrogen can cause impotence, ejaculation delay and inability to ejaculate in males, even if ejaculation is only a small amount of semen. Use adrenocortical hormone to female menstruation, menopause, male hormone can cause menstruation in women postpone, aphrodisia, and masculine.
Sedative-hypnotic long-term use or abuse of non-barbiturate sedative phenobarbital and sleeping pills, may cause menstrual cycle and ovulation disorders in women, men may experience decreased libido, impotence or loss of orgasm. Chlorpromazine effect on various segments of the nervous system has, for example, on the hypothalamus has increased prolactin, suppression of gonadotropin secretion, lead to a reduction of estrogen and testosterone secretion.
Antihypertensive drug reserpine is a common drug for treatment of hypertension, catecholamine depletion that can enable organizations to produce significant sedation, which indirectly reduces sexual desire. Long-term use of antihypertensive drugs can affect the hypothalamus pituitary function, thereby suppressing sperm production.
Anesthesia and analgesics such as morphine, dolantin, heroin can interfere with regulation of hypothalamic-pituitary system process, the penis cannot get an erection or erectile dysfunction is not so cannot complete the process of sexual intercourse, ejaculation disorder caused, leading to infertility.
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